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Upon erythropoietin binding, this receptor activates jak2 tyrosine kinase which activates different intracellular pathways including rasmap kinase, phosphatidylinositol 3kinase and stat transcription factors.

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This Test Is A Thirdorder Test And Should Be Ordered When The Patient Meets The Following Criteria Diagnosis Of Lifelong And Sustained Erythrocytosis, Jak2 V617f Is Negative And Serum Erythropoietin Levels Are Decreased To Normal.

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